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KMID : 0374019950180020105
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Ewha Medical Journal
1995 Volume.18 No. 2 p.105 ~ p.116
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Serum CEA in Non-Small Lung Cancer Patients
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Abstract
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Serum levels of carcinoembryonic antigen (CEA) were determined in 65 patients with non-small cell lung to investigate the correlation with clinico-pathologic characteristics. The most common histologic type was adenocarcinoma(44.6%), followed by
squamous cell carcinoma(41.5%) and large cell carcinoma(9.2%). Many patients were in unresectable advanced stage(IIIB:21.5%, IV:46.2%). Serum CEA was positive (defined as>10gn/ml) in 28 patients (43.1%). The positivity of serum CEA was
significantly
higher in adenocarcinoma (69.0%) than that in sqaumous cell carcinoma(25.9%) and large cell carcinoma(0.0%) (P=0.0004). There was no statistically significant difference in positivity CEA according to stages. Serum CEA level dose not seem to be
selective or specific standard tumor marker of non-small cell lung cancer patients. However, it may be useful as prognostic marker or monitor of treatment results, especially in adenocarcinoma.
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